| 陈礼辉,卢生昌,吴慧,渠昊帆.竹纤维素基黏附材料的制备及其湿组织黏附性能研究[J].中国造纸,2026,45(8):95-103 |
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| 竹纤维素基黏附材料的制备及其湿组织黏附性能研究 |
| Study on the Fabrication of Bamboo Cellulose-based Adhesive Materials and Its Wet Tissue Adhesion Property |
| 收稿日期：2026-06-10 修订日期：2026-06-30 |
| DOI：10.11980/j.issn.0254-508X.2026.08.010 |
| 关键词: 竹纤维 纤维素改性 黏附材料 湿组织黏附 |
| Key Words:bamboo fiber cellulose modification adhesive material wet tissue adhesion |
| 基金项目:国家自然科学基金（22278071，32401680）。 |
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| 摘要:为实现竹材高值化应用，针对目前纤维素基组织黏合剂存在湿黏附性能差的问题，本研究以竹纤维素纤维为原料制备羧甲基纤维素（CMC），通过甲基丙烯酸酐酯化改性制得可光交联的羧甲基纤维素甲基丙烯酸酯（CMC-MA），再与丙烯酸（AA）及含邻苯二酚基团的多巴单体（DMA）在蓝光下共聚，构建了具有共价键、氢键及π-π堆叠等多重交联网络的竹纤维素基黏附材料，系统考察了CMC-MA质量分数（0.5%~2.0%）对材料溶胀、力学及黏附性能的调控规律。结果表明，不同CMC-MA质量分数下，竹纤维素基黏附材料的平衡溶胀率为6.3~21.3 g/g，拉伸应力为3.1~5.7 MPa，断裂伸长率为180.4%~306.5%；其对湿态猪皮组织具有良好的黏附性能（剪切黏附强度23 kPa，界面韧性150 J/m2），显著优于商用组织黏合剂。离体器官密封实验结果表明，竹纤维素基黏附材料可承受模拟猪心脏200次周期性扩张收缩而不脱落，并可在猪胃酸泄漏模型中实现轻压5 s快速止漏密封，48 h后仍能维持牢固黏附和密封，且无细胞毒性。 |
| Abstract:To achieve high-value applications of bamboo， and to address the poor wet adhesion performance of current cellulose-based tissue adhesives， carboxymethyl cellulose (CMC) was prepared from bamboo cellulose fibers in this study. Through methacrylate esterification modification, a photo-crosslinkable carboxymethyl cellulose methacrylate (CMC-MA) was synthesized, then it was copolymerized with acrylic acid (AA) and the catechol-containing monomer dopa (DMA) under blue light to construct a bamboo cellulose-based adhesive material which featured a multi-crosslinked network comprising covalent bonds, hydrogen bonds, and π-π stacking. The study systematically investigated the regulation of material properties by varying the CMC-MA mass fraction (0.5%~2.0%). The resulting bamboo cellulose-based adhesive material exhibited equilibrium swelling ratios ranging from 6.3 to 21.3 g/g, tensile strengths from 3.1 to 5.7 MPa, and elongations at break from 180.4% to 306.5%. The optimized bamboo cellulose-based adhesive material demonstrated strong adhesion to moist porcine skin, with a shear strength of 23 kPa and an interfacial toughness of 150 J/m2, outperforming commercial tissue adhesives. The results of ex vivo organ sealing tests showed that the bamboo cellulose-based adhesive material withstood 200 cycles of cyclic expansion and contraction in a porcine heart model without detaching, and achieved rapid sealing under light pressure within 5 s in a simulated gastric acid leakage model, maintaining efficacy for 48 h， with no cytotoxicity. |
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